BDBM173822 US9102591, 2-chloro-N-[2-(4-pyridyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]ethyl]benzamide::US9649308, 2-chloro-N-[2-(4-pyridyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]ethyl]benzamide

SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1ccccc1Cl)c1ccncc1

InChI Key InChIKey=WEBMYSIDXGVBKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173822   

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM173822(US9102591, 2-chloro-N-[2-(4-pyridyl)-2-[2-(trifluo...)
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM173822(US9102591, 2-chloro-N-[2-(4-pyridyl)-2-[2-(trifluo...)
Affinity DataIC50: 30nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent