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BDBM17426 1,2,4-Triazole Compound, 84::5-[(3-methylbut-2-en-1-yl)sulfanyl]-N-(2-phenylphenyl)-4H-1,2,4-triazol-3-amine

SMILES: CC(C)=CCSc1nnc(Nc2ccccc2-c2ccccc2)[nH]1

InChI Key: InChIKey=TYVISOOKEXZEEY-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17426   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM17426
PNG
(1,2,4-Triazole Compound, 84 | 5-[(3-methylbut-2-en...)
Show SMILES CC(C)=CCSc1nnc(Nc2ccccc2-c2ccccc2)[nH]1
Show InChI InChI=1S/C19H20N4S/c1-14(2)12-13-24-19-21-18(22-23-19)20-17-11-7-6-10-16(17)15-8-4-3-5-9-15/h3-12H,13H2,1-2H3,(H2,20,21,22,23)
PDB
MMDB

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Similars

Article
PubMed
480n/an/an/an/an/an/an/an/a



GSK



Assay Description
MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...


J Med Chem 50: 3777-85 (2007)


Article DOI: 10.1021/jm061182w
BindingDB Entry DOI: 10.7270/Q2B856D7
More data for this
Ligand-Target Pair