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BDBM174890 US9102669, 82

SMILES: OCCn1cc(cn1)-c1ccc(nn1)N1CCC(CC1)n1ncc2ccc(F)cc12

InChI Key: InChIKey=VDHRRGJZIXAUGT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174890   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Stearoyl-CoA desaturase 1 (SCD1)


(Rattus norvegicus (Rat))
BDBM174890
PNG
(US9102669, 82)
Show SMILES OCCn1cc(cn1)-c1ccc(nn1)N1CCC(CC1)n1ncc2ccc(F)cc12
Show InChI InChI=1S/C21H22FN7O/c22-17-2-1-15-12-24-29(20(15)11-17)18-5-7-27(8-6-18)21-4-3-19(25-26-21)16-13-23-28(14-16)9-10-30/h1-4,11-14,18,30H,5-10H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 53n/an/an/an/an/a25



Janssen Pharmaceutica NV

US Patent


Assay Description
The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...


US Patent US9102669 (2015)


BindingDB Entry DOI: 10.7270/Q2BC3X9V
More data for this
Ligand-Target Pair