BDBM175095 US9115102, Apratastat

SMILES CC1(C)SCCN(C1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1

InChI Key InChIKey=MAVDNGWEBZTACC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 175095   

TargetInterstitial collagenase(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175095(US9115102, Apratastat)
Affinity DataIC50:  145nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-1(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175095(US9115102, Apratastat)
Affinity DataIC50:  10nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175095(US9115102, Apratastat)
Affinity DataIC50:  5nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175095(US9115102, Apratastat)
Affinity DataIC50:  85nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175095(US9115102, Apratastat)
Affinity DataIC50:  71nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175095(US9115102, Apratastat)
Affinity DataIC50:  82nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent