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BDBM175321 (E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N'-(4-methylbenzylidene) benzohydrazide (16)

SMILES: Cc1ccc(\C=N\NC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1

InChI Key: InChIKey=SUUKRSNFVOHKTF-AFUMVMLFSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175321   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM175321
PNG
((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...)
Show SMILES Cc1ccc(\C=N\NC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1
Show InChI InChI=1S/C24H22N4O/c1-15-4-6-18(7-5-15)14-25-28-24(29)20-10-8-19(9-11-20)23-26-21-12-16(2)17(3)13-22(21)27-23/h4-14H,1-3H3,(H,26,27)(H,28,29)/b25-14+
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 1.83E+4n/an/an/an/an/an/a



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...


Bioorg Chem 64: 29-36 (2016)

More data for this
Ligand-Target Pair