BDBM175369 8-[4-{2-(Diethylaminoethylamino)-2-oxoethoxy}-phenyl]-1,3-dimethylxanthine (13b, RB-421)

SMILES CCN(CC)CCNC(=O)COc1ccc(cc1)-c1nc2n(C)c(=O)n(C)c(=O)c2[nH]1

InChI Key InChIKey=HTRTYJCHNCFLGF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 175369   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Panjab University

LigandPNGBDBM175369(8-[4-{2-(Diethylaminoethylamino)-2-oxoethoxy}-phen...)
Affinity DataKi:  63nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Panjab University

LigandPNGBDBM175369(8-[4-{2-(Diethylaminoethylamino)-2-oxoethoxy}-phen...)
Affinity DataKi:  298nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Panjab University

LigandPNGBDBM175369(8-[4-{2-(Diethylaminoethylamino)-2-oxoethoxy}-phen...)
Affinity DataKi:  968nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3 [I248L](Homo sapiens (Human))
Panjab University

LigandPNGBDBM175369(8-[4-{2-(Diethylaminoethylamino)-2-oxoethoxy}-phen...)
Affinity DataKi:  8.35E+3nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed