BDBM175671 US9688672, Example 440

SMILES C[C@H](Nc1ncc(F)c(n1)N1[C@@H](CF)COC1=O)c1cnc(s1)-c1ccnc(F)c1

InChI Key InChIKey=LAVCAOAYAIPTIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175671   

LigandPNGBDBM175671(US9688672, Example 440)
Affinity DataIC50: 172nMpH: 7.5 T: 2°CAssay Description:The IDH1 (R132H) mutant catalyzes the reduced form of NADP+(NADPH) and α-ketoglutarate (α-KG) to form nicotinamide adenine dinucleotide pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent