BDBM175833 US9688684, Compound 30: {4-[8-(2,5-Difluoro-phenyl)-5,6-dihydro-8H-tetrazolo[1,5-a]pyrazin-7-ylmethyl]-phenyl}-dimethyl-amine

SMILES CN(C)c1ccc(CN2CCn3nnnc3C2c2cc(F)ccc2F)cc1

InChI Key InChIKey=ZSEBSSJRXFPUNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175833   

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandPNGBDBM175833(US9688684, Compound 30: {4-[8-(2,5-Difluoro-phenyl...)
Affinity DataIC50: 2.50E+4nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent