BDBM175840 US9688684, Compound 37: 7-(2,5-Difluoro-benzyl)-8-(3-fluoro-phenyl)-5,6,7,8-tetrahydro-tetrazolo[1,5-a]pyrazine

SMILES Fc1cccc(c1)C1N(Cc2cc(F)ccc2F)CCn2nnnc12

InChI Key InChIKey=AVEMSAPCCIVACI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175840   

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandPNGBDBM175840(US9688684, Compound 37: 7-(2,5-Difluoro-benzyl)-8-...)
Affinity DataIC50: 2.50E+4nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent