BDBM175853 US9688684, Compound 50: 7-(2,3-Difluoro-benzyl)-8-thiophen-2-yl-5,6,7,8-tetrahydro-tetrazolo[1,5-a]pyrazine

SMILES Fc1cccc(CN2CCn3nnnc3C2c2cccs2)c1F

InChI Key InChIKey=HIXRJJDBDZUWKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175853   

TargetNuclear receptor ROR-gamma [238-497](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM175853(US9688684, Compound 50: 7-(2,3-Difluoro-benzyl)-8-...)
Affinity DataIC50:  2.50E+4nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent