BDBM175885 US9688684, Compound 82: (3-Bromo-phenyl)-[8-(3-fluoro-phenyl)-5,6-dihydro-8H-tetrazolo[1,5-a]pyrazin-7-yl]-methanone

SMILES Fc1cccc(c1)C1N(CCn2nnnc12)C(=O)c1cccc(Br)c1

InChI Key InChIKey=NLHOKXUMLCNGGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175885   

TargetNuclear receptor ROR-gamma [238-497](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM175885(US9688684, Compound 82: (3-Bromo-phenyl)-[8-(3-flu...)
Affinity DataIC50:  2.50E+4nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent