BDBM175958 US9688684, Compound 155: 7-(1-Ethyl-1H-pyrazol-4-ylmethyl)-8-(3-isopropyl-1-phenyl-1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-tetrazolo[1,5-a]pyrazine

SMILES CCn1cc(CN2CCn3nnnc3C2c2cn(nc2C(C)C)-c2ccccc2)cn1

InChI Key InChIKey=QEGBGOAMDCPBMZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175958   

TargetNuclear receptor ROR-gamma [238-497](Human)
Merck Patent

US Patent
LigandPNGBDBM175958(US9688684, Compound 155: 7-(1-Ethyl-1H-pyrazol-4-y...)
Affinity DataIC50: 2.50E+4nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
US Patent