BDBM175960 US9688684, Compound 157: 8-(3-Isopropyl-1-phenyl-1H-pyrazol-4-yl)-7-(1,3,5-trimethyl-1H-pyrazol-4-ylmethyl)-5,6,7,8-tetrahydro-tetrazolo[1,5-a]pyrazine

SMILES CC(C)c1nn(cc1C1N(Cc2c(C)nn(C)c2C)CCn2nnnc12)-c1ccccc1

InChI Key InChIKey=SKLKCYDAFGOFBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175960   

TargetNuclear receptor ROR-gamma [238-497](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM175960(US9688684, Compound 157: 8-(3-Isopropyl-1-phenyl-1...)
Affinity DataIC50:  2.50E+4nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent