BDBM176339 US9688696, 55

SMILES CC(c1ccccc1)n1ncc2[nH]c(nc12)-c1ccc(cc1)N1CCN(CC1)C(=O)Nc1c(Cl)cc(cc1Cl)N1CCCC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176339   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM176339(US9688696, 55)
Affinity DataIC50:  15nMpH: 7.4 T: 2°CAssay Description:DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent