BDBM176539 US9688710, 99 (2S,3R,4R,5S,6R)-2-(3-(4-(4-(diethylamino)butyl)benzyl)-4-methylphenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol

SMILES CCN(CC)CCCCc1ccc(Cc2cc(ccc2C)[C@@H]2O[C@H](SC)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=XAWBJPVGEALSFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176539   

TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 176539BDBM176539(US9688710, 99 (2S,3R,4R,5S,6R)-2-(3-(4-(4-(diethyl...)
Affinity DataIC50: 10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 2 (SGLT2; accession number P31639; GI:400337) was cloned into pIRESpuro2 vector for mammalian expression (co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

TargetSodium/glucose cotransporter 1(Human)
Lexicon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 176539BDBM176539(US9688710, 99 (2S,3R,4R,5S,6R)-2-(3-(4-(4-(diethyl...)
Affinity DataIC50: 10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent