BDBM17664 (2S)-2-amino-3-(phosphonooxy)propanoic acid::CHEMBL284377::L-SOP::L-serine O-phosphate

SMILES N[C@@H](COP(O)(O)=O)C(O)=O

InChI Key InChIKey=BZQFBWGGLXLEPQ-REOHCLBHSA-N

Data  5 KI  1 IC50  5 EC50

PDB links: 1815 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 17664   

TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataKi:  2.30E+3nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataKi:  2.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
CNS Research

Curated by ChEMBL
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataEC50:  1.60E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR7 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataEC50:  1.30E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in humanMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
CNS Research

Curated by ChEMBL
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataEC50:  2.70E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR6 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2 [44-750](Homo sapiens (Human))
Nci-Fcrdc

LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataIC50:  5.23E+5nMpH: 7.4 T: 2°CAssay Description:The inhibition concentration values of GCPII were determined using the radioenzymatic assay with [3H] NAAG (radiolabeled on the terminal glutamate). ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataEC50:  4.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair