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BDBM17680 2-aminobenzimidazole, 5::N-(4-chlorophenyl)-5-[(6,7-dimethoxyquinazolin-4-yl)oxy]-1H-1,3-benzodiazol-2-amine

SMILES: COc1cc2ncnc(Oc3ccc4nc(Nc5ccc(Cl)cc5)[nH]c4c3)c2cc1OC

InChI Key: InChIKey=DEYZENHJMHXQGD-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17680   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM17680
PNG
(2-aminobenzimidazole, 5 | N-(4-chlorophenyl)-5-[(6...)
Show SMILES COc1cc2ncnc(Oc3ccc4nc(Nc5ccc(Cl)cc5)[nH]c4c3)c2cc1OC
Show InChI InChI=1S/C23H18ClN5O3/c1-30-20-10-16-18(11-21(20)31-2)25-12-26-22(16)32-15-7-8-17-19(9-15)29-23(28-17)27-14-5-3-13(24)4-6-14/h3-12H,1-2H3,(H2,27,28,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
8 -10.9n/an/an/an/an/a7.522



Amgen



Assay Description
The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...


J Med Chem 50: 4351-4373 (2007)


Article DOI: 10.1021/jm070034i
BindingDB Entry DOI: 10.7270/Q21V5C74
More data for this
Ligand-Target Pair