BDBM17697 2-aminobenzoxazole, 22::4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-N-methylpyridine-2-carboxamide

SMILES: CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)c(OC[C@@H]5CCCN5C)c4)nc3c2)ccn1

InChI Key: InChIKey=KMNCFOUKJYOZIF-UHFFFAOYSA-N

Data: 1 KI  10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 17697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	720	n/a	n/a	n/a	n/a	7.5	22
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Angiopoietin-1 receptor (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.18E+3	n/a	n/a	n/a	n/a	7.5	22
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Insulin-like growth factor 1 receptor (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.01E+3	n/a	n/a	n/a	n/a	7.5	22
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Macrophage colony-stimulating factor 1 receptor (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	7.5	22
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Mast/stem cell growth factor receptor Kit (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	7.5	22
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Tyrosine-protein kinase Lck (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM17697 (4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80	-11.5	4.60	n/a	n/a	n/a	n/a	7.5	22
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