BDBM1773 US10280174, Comparative Compound 1::US8476284, 4::US8497277, 13::US8497277, 4::US9133201, 13::US9133201, 14::US9133201, 4::US9975882, comparative compound A

SMILES: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCCN(C1)C(=O)C=C

InChI Key: InChIKey=XYFPWWZEPKGCCK-UHFFFAOYSA-N

Data: 2 KI  11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 1773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase TXK (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.720	n/a	n/a	n/a	n/a	7.4	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.720	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.5	n/a	n/a	n/a	n/a	7.4	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.720	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.5	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.4	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM1773 (US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...) Show SMILES Show InChI	GoogleScholar	UniChem		97	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
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