BDBM177362 US9120749, 728

SMILES CN1CCN(C[C@@H]2CC[C@H](C2)Nc2c(cnc3ccc(cc23)-c2cc(Cl)c(O)c(Cl)c2)C(C)=O)CC1

InChI Key InChIKey=CJLPKWRRMUIYHI-WIYYLYMNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177362   

TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Oncotherapy Science

US Patent
LigandPNGBDBM177362(US9120749, 728)
Affinity DataIC50:  5.70nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In DepthDetails US Patent