BDBM177375 US9120749, 741::US9120749, 742

SMILES CN(C)CC[C@H]1CC[C@@H](CC1)Nc1c(cnc2ccc(cc12)-c1cc(F)c(O)c(Cl)c1)C(C)=O

InChI Key InChIKey=COGGEEGQBVOGAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177375   

TargetMaternal embryonic leucine zipper kinase(Human)
Oncotherapy Science

US Patent
LigandPNGBDBM177375(US9120749, 742 | US9120749, 741)
Affinity DataIC50: 4.40nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetMaternal embryonic leucine zipper kinase(Human)
Oncotherapy Science

US Patent
LigandPNGBDBM177375(US9120749, 742 | US9120749, 741)
Affinity DataIC50: 4.80nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent