BDBM1774 US10894048, Ref. Ex Comp. 1::US8476284, 13

SMILES: Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@H]1CCCN(C1)C(=O)C=C

InChI Key: InChIKey=XYFPWWZEPKGCCK-UHFFFAOYSA-N

Data: 19 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 1774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Blk (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-4 (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.5	n/a	n/a	n/a	n/a	7.4	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 2 (Human)	BDBM1774 (US8476284, 13 | US10894048, Ref. Ex Comp. 1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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