BDBM17744 2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}amino)pyrimidin-4-yl]-N-(2,4-dimethoxyphenyl)carbamate::2-aminopyrimidine carbamate, 43

SMILES: Cc1cccc(c1OC(=O)N(c2ccc(cc2OC)OC)c3ccnc(n3)Nc4cc(c(c(c4)OC)OCCCN5CCN(CC5)C)OC)C

InChI Key: InChIKey=VSJXTUFWPAOYLC-UHFFFAOYSA-N

Data: 13 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 17744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.5	22
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Angiopoietin-1 receptor (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	7.5	22
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Hepatocyte growth factor receptor (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	7.5	22
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Fibroblast growth factor receptor 1 (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	7.5	22
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Insulin-like growth factor 1 receptor (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	7.5	22
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Tyrosine-protein kinase ZAP-70 (Mouse)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	370	n/a	n/a	n/a	n/a	7.5	22
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM17744 (2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
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