BDBM17747 (3Z)-3-{[4-(dimethylamino)phenyl]methylidene}-2,3-dihydro-1H-indol-2-one::CHEMBL328710::SU 4312::SU4312

SMILES: CN(C)c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1

InChI Key: InChIKey=UAKWLVYMKBWHMX-UHFFFAOYSA-N

Data: 3 KI  21 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 17747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage colony-stimulating factor 1 receptor [538-972] ()	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	7.5	22
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Epidermal growth factor receptor (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Mouse)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Luciferin 4-monooxygenase (Common eastern firefly)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Luciferin 4-monooxygenase (Common eastern firefly)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Luciferin 4-monooxygenase (Common eastern firefly)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Luciferin 4-monooxygenase (Common eastern firefly)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Luciferin 4-monooxygenase (Common eastern firefly)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [538-678,753-922] (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [538-678,753-922] (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	7.5	22
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Alpha-synuclein (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Amyloid-beta precursor protein (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Microtubule-associated protein tau (Human)	BDBM17747 (CHEMBL328710 | (3Z)-3-{[4-(dimethylamino)phenyl]me...) Show SMILES Show InChI	GoogleScholar	UniChem		262	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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