BDBM177475 US9120749, 841

SMILES CN(C)C[C@H]1CC[C@@H](CC1)Nc1c(cnc2cc(c(cc12)-c1cc(F)c(O)c(Cl)c1)C(F)(F)F)C(=O)C1CC1

InChI Key InChIKey=OWSODXICOGXEQP-RZDIXWSQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177475   

TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Oncotherapy Science

US Patent
LigandPNGBDBM177475(US9120749, 841)
Affinity DataIC50:  770nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In DepthDetails US Patent