BDBM177490 US9120749, 856

SMILES CN1CCN(CC1)c1ccc(Nc2c(cnc3cc(C)c(cc23)-c2cc(F)c(O)c(Cl)c2)C(C)=O)cn1

InChI Key InChIKey=BSUFGKZXTSIRRD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177490   

TargetMaternal embryonic leucine zipper kinase(Human)
Oncotherapy Science

US Patent
LigandPNGBDBM177490(US9120749, 856)
Affinity DataIC50: 460nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent