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BDBM177753 US9120781, 9

SMILES: CCNC1=N[C@H]2[C@H](C[C@H](CO)[C@@H](O)[C@@H]2O)O1

InChI Key: InChIKey=PURJRQUOTKSCNB-QMGXLNLGSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177753   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-acetyl-beta-D-glucosaminidase (O-GlcNAcase)


(Homo sapiens (Human))
BDBM177753
PNG
(US9120781, 9)
Show SMILES CCNC1=N[C@H]2[C@H](C[C@H](CO)[C@@H](O)[C@@H]2O)O1
Show InChI InChI=1S/C10H18N2O4/c1-2-11-10-12-7-6(16-10)3-5(4-13)8(14)9(7)15/h5-9,13-15H,2-4H2,1H3,(H,11,12)/t5-,6+,7+,8-,9-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
0.600 -12.6n/an/an/an/an/a7.025



Simon Fraser University; Merck Sharp & Dohme Corp.; Alectos Therapeutics Inc.

US Patent


Assay Description
Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety...


US Patent US9120781 (2015)


BindingDB Entry DOI: 10.7270/Q2DZ072S
More data for this
Ligand-Target Pair