BDBM17779 2-[(hydroxycarbamoyl)methyl]pentanedioic acid::CHEMBL65043::hydroxamate, 41

SMILES ONC(=O)CC(CCC(O)=O)C(O)=O

InChI Key InChIKey=PILHIJIJVLWKNF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17779   

TargetGlutamate carboxypeptidase 2 [44-750](Homo sapiens (Human))
Mgi Pharma

LigandPNGBDBM17779(2-[(hydroxycarbamoyl)methyl]pentanedioic acid | CH...)
Affinity DataIC50:  220nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17779(2-[(hydroxycarbamoyl)methyl]pentanedioic acid | CH...)
Affinity DataEC50:  220nMAssay Description:Concentration of the compound required for the neuroprotective effect determined by inhibition of GCP IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17779(2-[(hydroxycarbamoyl)methyl]pentanedioic acid | CH...)
Affinity DataIC50:  220nMAssay Description:Inhibition of Glutamate carboxypeptidase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed