BDBM178305 US9120812, 90

SMILES CCN1CC(C)(C)Oc2nc(nc(-c3ccc(NC(=O)Nc4cc(C)nc(C)n4)c(F)c3)c2C1=O)N1CC2CCC(C1)O2

InChI Key InChIKey=HHLDFURHJAEBDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178305   

TargetSerine/threonine-protein kinase mTOR(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 178305BDBM178305(US9120812, 90)
Affinity DataIC50: 450nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent