BDBM178368 US9120812, 153

SMILES CC1(C)CN(C2CCOCC2)C(=O)c2c(O1)nc(nc2-c1ccc(NC(=O)Nc2ccon2)c(F)c1)N1CC2CCC(C1)O2

InChI Key InChIKey=OTHOAKOLOMZDHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 178368   

TargetSerine/threonine-protein kinase mTOR(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 178368BDBM178368(US9120812, 153)
Affinity DataIC50: 31nMpH: 7.5 T: 2°CAssay Description:The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 178368BDBM178368(US9120812, 153)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:The test uses a lucifeurerin/luciferase system to measure the concentration of ATP and its consumption during the enzymatic reaction. The test is per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
US Patent