BDBM17847 CHEMBL327579::pyridine-2-carboxylic acid inhibitor, 1::tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin-3-yl]carbamate

SMILES: CC(C)(C)OC(=O)Nc1cccnc1C(=O)Nc2nccs2

InChI Key: InChIKey=QBMYJIFXSXKPFS-UHFFFAOYSA-N

Data: 8 IC50  6 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 17847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.5	22
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Methionine aminopeptidase 2 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase (Escherichia coli (strain K12))	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
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Methionine aminopeptidase 1 (Baker's yeast)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Human)	BDBM17847 (tert-butyl N-[2-(1,3-thiazol-2-ylcarbamoyl)pyridin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair