BDBM179417 US10307413, Compound 328::US10391089, Compound 328::US10980794, Cmpd No 328::US9675614, 328

SMILES O[C@@H](CNC(=O)c1ccc2CCCNc2c1O)CN1CCc2ccccc2C1

InChI Key InChIKey=KCURXJGMKPRBSY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 179417   

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM179417(US9675614, 328 | US10307413, Compound 328 | US1039...)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM179417(US9675614, 328 | US10307413, Compound 328 | US1039...)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2020
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM179417(US9675614, 328 | US10307413, Compound 328 | US1039...)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Epizyme

US Patent
LigandPNGBDBM179417(US9675614, 328 | US10307413, Compound 328 | US1039...)
Affinity DataIC50: 5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent