BDBM179481 US9675697, Cpd. No. 73

SMILES COc1cc2c(cc1-c1c(C)noc1C)[nH]c1nc(C)nc(-c3ccnc4ccccc34)c21

InChI Key InChIKey=AEANZCXROGPSBY-UHFFFAOYSA-N

Data  9 KI  4 IC50  36 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 49 hits for monomerid = 179481   

TargetBromodomain-containing protein 3(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  0.690nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  0.730nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 1/2 (P24 to P416 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  0.900nMAssay Description:Binding affinity to human partial length BRD2 bromodomain 2 isoform 1 (349 to 460 residues) expressed in bacterial expression system by BROMOscan ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to human partial length BRD2 bromodomain 1/2 isoform 1 (K71 to D455 residues) by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  1.40nMAssay Description:Inhibition of FAM-labeled ZBA248 binding to recombinant human N-terminal His6-tagged BRD4 bromodomain 2 (333 to 460 residues) expressed in Rosetta2 D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  1.80nMAssay Description:Binding affinity to human partial length BRD4 bromodomain 1/2 long isoform (N44 to E460 residues) expressed in bacterial expression system by BROMOsc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  2nMAssay Description:Binding affinity to human partial length BRD4 bromodomain 2 long isoform (K333 to E460 residues) expressed in bacterial expression system by BROMOsca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  2nMAssay Description:Binding affinity to human partial length BRD3 bromodomain 1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 3 [326-398](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  2.60nM ΔG°:  -11.7kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  4.5nMAssay Description:Binding affinity to human partial length BRD2 bromodomain 1 long isoform (72 to 205 residues) expressed in bacterial expression system by BROMOscan a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  5.5nMAssay Description:Binding affinity to human partial length BRDT bromodomain 2 isoform b (K250 to E382 residues) expressed in bacterial expression system by BROMOscan a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of FAM-labeled ZBA248 binding to recombinant human N-terminal His6-tagged BRD4 bromodomain 2 (333 to 460 residues) expressed in Rosetta2 D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2 [364-436](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  7.80nM ΔG°:  -11.1kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  8.20nMAssay Description:Inhibition of FAM-labeled ZBA248 binding to recombinant human N-terminal His6-tagged BRD4 bromodomain 1 (44 to 168 residues) expressed in Rosetta2 DE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  8.20nMAssay Description:Inhibition of FAM-labeled ZBA248 binding to recombinant human BRD4 bromodomain 1 (44 to 168 residues) expressed in Rosetta2 Escherichia coli DE3 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  8.40nMAssay Description:Binding affinity to recombinant human BRD4 bromodomain 1 (44 to 168 residues) by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2 [364-436](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  8.70nM ΔG°:  -11.0kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  9.70nMAssay Description:Binding affinity to human partial length BRDT bromodomain 1/2 isoform b (K250 to E382 residues) expressed in bacterial expression system by BROMOscan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  10nM ΔG°:  -10.9kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  15nMAssay Description:Binding affinity to human partial length BRDT bromodomain 1 isoform b (N21 to E137 residues) expressed in bacterial expression system by BROMOscan as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2 [91-163](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  16nM ΔG°:  -10.6kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataIC50: 28nMAssay Description:Inhibition of FAM-labeled ZBA248 binding to recombinant human N-terminal His6-tagged BRD4 bromodomain 1 (44 to 168 residues) expressed in Rosetta2 DE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataIC50: 28nMAssay Description:Inhibition of FAM-labeled ZBA248 binding to recombinant human BRD4 bromodomain 1 (44 to 168 residues) expressed in Rosetta2 Escherichia coli DE3 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [75-147](Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKi:  35nM ΔG°:  -10.2kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetCREB-binding protein(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  520nMAssay Description:Binding affinity to human partial length CREBBP (R1081 to G1197 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  550nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human PLK4 (M1 to S273 residues) expressed in mammalian expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BAZ2B (S2054 to S2168 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain and WD repeat-containing protein 1(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length WDR9 bromodomain 2 (A1310 to E1430 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPeregrin(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BRPF1 (E627 to G740 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTranscription initiation factor TFIID subunit 1(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 1(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProbable global transcription activator SNF2L2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2B(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length ATAD2B (Q955 to R1082 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length PCAF (G715 to D831 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 2 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTranscription intermediary factor 1-alpha(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length TRIM24 expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length ATAD2A (Q981 to R1108 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTranscription activator BRG1(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length SMARCA4 (A1448 to S1575 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProtein polybromo-1(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length PBRM1 bromodomain 5 (S645 to D766 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 9(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BRD9 (R130 to V259 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 7(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BRD7 (L125 to R254 residues) expressed in mammalian expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNucleosome-remodeling factor subunit BPTF(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length FALZ (S2791 to H2911 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 8(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BRD8 bromodomain 2 (D1095 to F1235 residues) expressed in mammalian expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BAZ2A (M1792 to L1905 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 8(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length BRD8 bromodomain 1 (S700 to F854 residues) expressed in mammalian expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2A(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179481BDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd: >4.00E+3nMAssay Description:Binding affinity to human partial length GCN5L2 (E726 to K837 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed