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BDBM179671 US9676701, 30 (trans)-2-(6-(2-fluoro-3-(trifluoromethyl)phenyl)pyridin-3-yl)cyclopropanamine hydrochloride

SMILES: N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(c1F)C(F)(F)F

InChI Key: InChIKey=DSUCQHXTBSUZLH-XWJGPBAUNA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 179671   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM179671
PNG
(US9676701, 30 (trans)-2-(6-(2-fluoro-3-(trifluorom...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(c1F)C(F)(F)F
Show InChI InChI=1/C15H12F4N2/c16-14-9(2-1-3-11(14)15(17,18)19)13-5-4-8(7-21-13)10-6-12(10)20/h1-5,7,10,12H,6,20H2/t10-,12+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
550 -8.53n/an/an/an/an/a7.425



Oryzon Genomics, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM179671
PNG
(US9676701, 30 (trans)-2-(6-(2-fluoro-3-(trifluorom...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(c1F)C(F)(F)F
Show InChI InChI=1/C15H12F4N2/c16-14-9(2-1-3-11(14)15(17,18)19)13-5-4-8(7-21-13)10-6-12(10)20/h1-5,7,10,12H,6,20H2/t10-,12+/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+3n/an/an/an/an/an/a7.5n/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM179671
PNG
(US9676701, 30 (trans)-2-(6-(2-fluoro-3-(trifluorom...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1cccc(c1F)C(F)(F)F
Show InChI InChI=1/C15H12F4N2/c16-14-9(2-1-3-11(14)15(17,18)19)13-5-4-8(7-21-13)10-6-12(10)20/h1-5,7,10,12H,6,20H2/t10-,12+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+3n/an/an/an/an/an/a7.5n/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair