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BDBM179744 US9676701, 55 (trans)-2-(6-(benzo[b]thiophen-3-yl)pyridin-3-yl)cyclopropanamine hydrochloride

SMILES: N[C@H]1C[C@@H]1c1ccc(nc1)-c1csc2ccccc12

InChI Key: InChIKey=HWWHEVQIIILHHL-OCCSQVGLSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 179744   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM179744
PNG
(US9676701, 55 (trans)-2-(6-(benzo[b]thiophen-3-yl)...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1csc2ccccc12
Show InChI InChI=1S/C16H14N2S/c17-14-7-12(14)10-5-6-15(18-8-10)13-9-19-16-4-2-1-3-11(13)16/h1-6,8-9,12,14H,7,17H2/t12-,14+/m1/s1
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem
US Patent
550 -8.53n/an/an/an/an/a7.425



Oryzon Genomics, S.A.

US Patent


Assay Description
Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair
Amine oxidase (flavin-containing) A


(Homo sapiens (Human))
BDBM179744
PNG
(US9676701, 55 (trans)-2-(6-(benzo[b]thiophen-3-yl)...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1csc2ccccc12
Show InChI InChI=1S/C16H14N2S/c17-14-7-12(14)10-5-6-15(18-8-10)13-9-19-16-4-2-1-3-11(13)16/h1-6,8-9,12,14H,7,17H2/t12-,14+/m1/s1
PDB

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UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+3n/an/an/an/an/an/a7.5n/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM179744
PNG
(US9676701, 55 (trans)-2-(6-(benzo[b]thiophen-3-yl)...)
Show SMILES N[C@H]1C[C@@H]1c1ccc(nc1)-c1csc2ccccc12
Show InChI InChI=1S/C16H14N2S/c17-14-7-12(14)10-5-6-15(18-8-10)13-9-19-16-4-2-1-3-11(13)16/h1-6,8-9,12,14H,7,17H2/t12-,14+/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
>1.00E+3n/an/an/an/an/an/a7.5n/a



Oryzon Genomics, S.A.

US Patent


Assay Description
Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...


US Patent US9676701 (2017)


BindingDB Entry DOI: 10.7270/Q27P8WJN
More data for this
Ligand-Target Pair