BDBM17983 1,4-benzoxazin-3-one, 20::N-{2-[6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl]ethyl}acetamide::diaminopyrimidine renin inhibitor compound, 6

SMILES: CCc1nc(N)nc(N)c1-c1ccc2OC(C)(C)C(=O)N(CCNC(C)=O)c2c1

InChI Key: InChIKey=GBXSOZDYCSBLQX-UHFFFAOYSA-N

Data: 5 IC50  1 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 17983   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Human)	BDBM17983 (diaminopyrimidine renin inhibitor compound, 6 | N-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Renin (Human)	BDBM17983 (diaminopyrimidine renin inhibitor compound, 6 | N-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	222	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Renin (Human)	BDBM17983 (diaminopyrimidine renin inhibitor compound, 6 | N-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Renin (Human)	BDBM17983 (diaminopyrimidine renin inhibitor compound, 6 | N-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Renin (Human)	BDBM17983 (diaminopyrimidine renin inhibitor compound, 6 | N-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair