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BDBM18 (3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-yl)amine;bromide::3,8-diamino-5-methyl-6-phenylphenanthridin-5-ium bromide::5-methyl-6-phenyl-phenanthridin-5-ium-3,8-diamine;bromide::5-methyl-6-phenylphenanthridin-5-ium-3,8-diamine;bromide::Dimidium bromide::MLS001074889::SMR000568409::cid_68207::ethidium bromide

InChI string: InChI=1S/C20H17N3/c1-23-19-12-15(22)8-10-17(19)16-9-7-14(21)11-18(16)20(23)13-5-3-2-4-6-13/h2-12,22H,21H2,1H3/p+1

SMILES: Cn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12

InChI Key: InChIKey=MRYUEHRAIMRPNB-UHFFFAOYSA-O

Data: 3 IC50  3 EC50  2 ITC

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 18   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RecName: Full=Zinc finger protein mex-5


(Caenorhabditis elegans)
BDBM18
PNG
((3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-y...)
Show SMILES Cn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Show InChI InChI=1S/C20H17N3/c1-23-19-12-15(22)8-10-17(19)16-9-7-14(21)11-18(16)20(23)13-5-3-2-4-6-13/h2-12,22H,21H2,1H3/p+1
KEGG

UniProtKB/SwissProt

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UniChem

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n/an/an/an/a 5.36E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
streptokinase A precursor


(Streptococcus pyogenes M1 GAS)
BDBM18
PNG
((3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-y...)
Show SMILES Cn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Show InChI InChI=1S/C20H17N3/c1-23-19-12-15(22)8-10-17(19)16-9-7-14(21)11-18(16)20(23)13-5-3-2-4-6-13/h2-12,22H,21H2,1H3/p+1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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PC sid
UniChem

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n/an/an/an/a 1.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair
Apoptotic peptidase activating factor 1


(Homo sapiens)
BDBM18
PNG
((3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-y...)
Show SMILES Cn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Show InChI InChI=1S/C20H17N3/c1-23-19-12-15(22)8-10-17(19)16-9-7-14(21)11-18(16)20(23)13-5-3-2-4-6-13/h2-12,22H,21H2,1H3/p+1
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Article
PCBioAssay
n/an/a>1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...


PubChem Bioassay (2011)

More data for this
Ligand-Target Pair
Caspase-9


(Homo sapiens (human))
BDBM18
PNG
((3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-y...)
Show SMILES Cn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Show InChI InChI=1S/C20H17N3/c1-23-19-12-15(22)8-10-17(19)16-9-7-14(21)11-18(16)20(23)13-5-3-2-4-6-13/h2-12,22H,21H2,1H3/p+1
PDB
MMDB

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PCBioAssay
n/an/a 7.89E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...


PubChem Bioassay (2011)

More data for this
Ligand-Target Pair
Apoptotic peptidase activating factor 1


(Homo sapiens)
BDBM18
PNG
((3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-y...)
Show SMILES Cn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Show InChI InChI=1S/C20H17N3/c1-23-19-12-15(22)8-10-17(19)16-9-7-14(21)11-18(16)20(23)13-5-3-2-4-6-13/h2-12,22H,21H2,1H3/p+1
PDB
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PCBioAssay
n/an/a 2.45E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...


PubChem Bioassay (2011)

More data for this
Ligand-Target Pair
POsterior Segregation family member (pos-1)


(Caenorhabditis elegans)
BDBM18
PNG
((3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-y...)
Show SMILES Cn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Show InChI InChI=1S/C20H17N3/c1-23-19-12-15(22)8-10-17(19)16-9-7-14(21)11-18(16)20(23)13-5-3-2-4-6-13/h2-12,22H,21H2,1H3/p+1
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n/an/an/an/a 1.35E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)

More data for this
Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 18
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kcal/mole
-TΔS°
kcal/mole
ΔH°
kcal/mole
log KpHTemp
°C
H1/H5-depleted chromatin

(Homo sapiens (human)-Homo sapiens (Human))
BDBM18
JPEG
((3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-y...)
DrugBank
GoogleScholar
KEGG
PDB
PC cid
PC sid
-6.621.47-8.134.937.520



Universite de Liege





Biochemistry 37: 9119-26 (1998)

DNA(calf thymus)

(Bos taurus (bovine))
BDBM18
JPEG
((3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-y...)
GoogleScholar
PC cid
PC sid
-7.020.441-7.425.207.520



Universite de Liege





Biochemistry 37: 9119-26 (1998)