BDBM180352 US9133168, Example 10c::US9133168, Example 6c::US9133168, Example 9c

SMILES CC1Cc2c(cccc2O)N1C(=O)Cc1nc(cc(=O)[nH]1)N1CCOCC1

InChI Key InChIKey=RZSZPVBJGJPQOH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 180352   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Sanofi

US Patent
LigandPNGBDBM180352(US9133168, Example 6c | US9133168, Example 9c | US...)
Affinity DataIC50: 22nMAssay Description:This test is based on measurement of the expression of AKT protein phosphorylated on serine 473 (P-AKT-S473) in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Sanofi

US Patent
LigandPNGBDBM180352(US9133168, Example 6c | US9133168, Example 9c | US...)
Affinity DataIC50: 24nMAssay Description:This test is based on measurement of the expression of AKT protein phosphorylated on serine 473 (P-AKT-S473) in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Sanofi

US Patent
LigandPNGBDBM180352(US9133168, Example 6c | US9133168, Example 9c | US...)
Affinity DataIC50: 115nMAssay Description:This test is based on measurement of the expression of AKT protein phosphorylated on serine 473 (P-AKT-S473) in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent