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BDBM180455 US8772323, 19

SMILES: Fc1ccc(cc1)-c1nc2ccc(cc2o1)C1=NNC(=O)C2CCC12

InChI Key: InChIKey=AGSYOHCROJWYKG-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180455   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM180455
PNG
(US8772323, 19)
Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2o1)C1=NNC(=O)C2CCC12
Show InChI InChI=1S/C19H14FN3O2/c20-12-4-1-10(2-5-12)19-21-15-8-3-11(9-16(15)25-19)17-13-6-7-14(13)18(24)23-22-17/h1-5,8-9,13-14H,6-7H2,(H,23,24)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/an/an/a 469n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair