BDBM18046 5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, 1::5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE::5-[(4-methylphenyl)sulfanyl]quinazoline-2,4-diamine::5-[(4-methylphenyl)sulfanyl]quinazoline-2,4-diamine, 2c::CHEMBL83547::GW578

SMILES: Cc1ccc(cc1)Sc2cccc3c2c(nc(n3)N)N

InChI Key: InChIKey=UOJFGEAPSYQDIP-UHFFFAOYSA-N

Data: 2 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 18046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Yeast)	BDBM18046 (CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	6.4	30
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Dihydrofolate reductase (Human)	BDBM18046 (CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	7.0	30
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Lysosomal acid glucosylceramidase (Human)	BDBM18046 (CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	5.5	37
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Dihydrofolate reductase (Escherichia coli)	BDBM18046 (CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM18046 (CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM18046 (CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli (strain K12))	BDBM18046 (CHEMBL83547 | 5-((4-methylphenyl)thio)-quinazoline...) Show SMILES Show InChI	GoogleScholar	UniChem		150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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