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BDBM180563 US8772323, 90

SMILES: COC(=O)c1ccc(cc1)-c1nc2ccc(cc2o1)C1=NNC(=O)CC1C

InChI Key: InChIKey=VRMGOIKUQIUNGI-UHFFFAOYNA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180563   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM180563
PNG
(US8772323, 90)
Show SMILES COC(=O)c1ccc(cc1)-c1nc2ccc(cc2o1)C1=NNC(=O)CC1C
Show InChI InChI=1/C20H17N3O4/c1-11-9-17(24)22-23-18(11)14-7-8-15-16(10-14)27-19(21-15)12-3-5-13(6-4-12)20(25)26-2/h3-8,10-11H,9H2,1-2H3,(H,22,24)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/an/an/a 763n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair