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BDBM180683 US8772323, 240

SMILES: CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC[C@@H]2CCCN2C(C)C)cc1

InChI Key: InChIKey=BHWCYYVRWYIONW-ZYZRXSCRSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 180683   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM180683
PNG
(US8772323, 240)
Show SMILES CCC1CC(=O)NN=C1c1ccc2nc(oc2c1)-c1ccc(OC[C@@H]2CCCN2C(C)C)cc1
Show InChI InChI=1S/C27H32N4O3/c1-4-18-15-25(32)29-30-26(18)20-9-12-23-24(14-20)34-27(28-23)19-7-10-22(11-8-19)33-16-21-6-5-13-31(21)17(2)3/h7-12,14,17-18,21H,4-6,13,15-16H2,1-3H3,(H,29,32)/t18?,21-/m0/s1
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Similars

Article
US Patent
n/an/an/an/a 186n/an/a7.437



Boehringer Ingelheim International GmbH

US Patent


Assay Description
MIN6 cells [Miyazaki J et al. Endocrinology. 1990 July; 127(1):126-32] were stably transfected with an expression vector for human GPR119 cDNA (Acc. ...


US Patent US8772323 (2014)


Article DOI: null
BindingDB Entry DOI: 10.7270/Q2639NHH
More data for this
Ligand-Target Pair