BDBM181035 US9133183, Example 101
SMILES CN(C)C(=O)Nc1cc(Oc2cc(F)c(NC(=O)N3CCN(C4CCOCC4)C3=O)cc2Cl)ccn1
InChI Key InChIKey=AWTMGZROWMENCS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 181035
TargetMacrophage colony-stimulating factor 1 receptor [538-972](Homo sapiens (Human))
Deciphera Pharmaceuticals
US Patent
Deciphera Pharmaceuticals
US Patent
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:Activity of unphosphorylated c-FMS kinase (uFMS, Seq. ID no. 1) was determined by following the production of ADP from the FMS kinase reaction with A...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Deciphera Pharmaceuticals
US Patent
Deciphera Pharmaceuticals
US Patent
Affinity DataIC50: >3.30E+3nMT: 2°CAssay Description:These tests measure the ability of compounds to inhibit the enzymatic activity of recombinant human c-Met/HGF receptor and VEGF receptor enzymatic ac...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMT: 2°CAssay Description:These tests measure the ability of compounds to inhibit the enzymatic activity of recombinant human c-Met/HGF receptor and VEGF receptor enzymatic ac...More data for this Ligand-Target Pair