BDBM181059 (E)-N'-(2-Hydroxybenzylidene)-4-(2-oxo-2H-chromen-3-yl)thiazole-2-carbohydrazide (7b)

SMILES Oc1ccccc1\C=N\NC(=O)c1nc(cs1)-c1cc2ccccc2oc1=O

InChI Key InChIKey=DNCDTDAVUMKQQN-UFFVCSGVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181059   

TargetProbable maltase-glucoamylase 2(Homo sapiens)
Babasaheb Bhimrao Ambedkar University (A Central University)

Curated by ChEMBL
LigandPNGBDBM181059((E)-N'-(2-Hydroxybenzylidene)-4-(2-oxo-2H-chro...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-nitro phenyl glucopyranoside as substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Jishou University

LigandPNGBDBM181059((E)-N'-(2-Hydroxybenzylidene)-4-(2-oxo-2H-chro...)
Affinity DataIC50:  3.72E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed