BDBM181062 (E)-N'-(3,5-Dichloro-2-hydroxybenzylidene)-4-(2-oxo-2Hchromen-3-yl)thiazole-2-carbohydrazide (7e)

SMILES Oc1c(Cl)cc(Cl)cc1\C=N\NC(=O)c1nc(cs1)-c1cc2ccccc2oc1=O

InChI Key InChIKey=DBCVETGEECJHRM-LIMNOBDPSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 181062   

TargetProbable maltase-glucoamylase 2(Homo sapiens)
Babasaheb Bhimrao Ambedkar University (A Central University)

Curated by ChEMBL
LigandPNGBDBM181062((E)-N'-(3,5-Dichloro-2-hydroxybenzylidene)-4-(...)
Affinity DataKi:  6.80E+3nMAssay Description:Non-competitive inhibition of alpha-glucosidase (unknown origin) using p-nitro phenyl glucopyranoside as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Jishou University

LigandPNGBDBM181062((E)-N'-(3,5-Dichloro-2-hydroxybenzylidene)-4-(...)
Affinity DataIC50:  6.24E+3nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable maltase-glucoamylase 2(Homo sapiens)
Babasaheb Bhimrao Ambedkar University (A Central University)

Curated by ChEMBL
LigandPNGBDBM181062((E)-N'-(3,5-Dichloro-2-hydroxybenzylidene)-4-(...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-nitro phenyl glucopyranoside as substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed