BDBM181447 US9139577, 3.008::US9708274, 3.008

SMILES Cc1cc(cc2ncnc(Nc3ccc(F)cc3OCC3CC3(F)F)c12)N=S(C)(C)=O

InChI Key InChIKey=JDRFTAABHLKNTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181447   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Evotec International

US Patent
LigandPNGBDBM181447(US9708274, 3.008 | US9139577, 3.008)
Affinity DataIC50: 5nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Evotec International

US Patent
LigandPNGBDBM181447(US9708274, 3.008 | US9139577, 3.008)
Affinity DataIC50: 5nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent