BDBM18166 (6S)-6-hydroxy-2-(4-nitronaphthalen-1-yl)-hexahydro-1H-pyrrolo[1,2-a]imidazolidine-1,3-dione::N-aryl-bicyclic hydantoin, 7c

SMILES O[C@H]1Cc2c(O)n(-c3ccc([N+]([O-])=O)c4ccccc34)c(=O)n2C1

InChI Key InChIKey=FUYZHQGVZXPEJY-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18166   

TargetAndrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM18166((6S)-6-hydroxy-2-(4-nitronaphthalen-1-yl)-hexahydr...)
Affinity DataKi:  4.30nM ΔG°:  -11.3kcal/mole EC50:  265nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2007
Entry Details Article
PubMed