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BDBM181984 US9145380, 187

SMILES: CC(C)(C)C#Cc1ccc(CCS(=O)(=O)Nc2ccccc2S(N)(=O)=O)cn1

InChI Key: InChIKey=NRYOGTRHDDJCKP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 181984   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E synthase 2


(Homo sapiens (Human))
BDBM181984
PNG
(US9145380, 187)
Show SMILES CC(C)(C)C#Cc1ccc(CCS(=O)(=O)Nc2ccccc2S(N)(=O)=O)cn1
Show InChI InChI=1S/C19H23N3O4S2/c1-19(2,3)12-10-16-9-8-15(14-21-16)11-13-27(23,24)22-17-6-4-5-7-18(17)28(20,25)26/h4-9,14,22H,11,13H2,1-3H3,(H2,20,25,26)
PDB

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antibodypedia
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PC sid
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Similars

US Patent
n/an/a 680n/an/an/an/a6.8n/a



AstraZeneca AB

US Patent


Assay Description
A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...


US Patent US9145380 (2015)


BindingDB Entry DOI: 10.7270/Q2XG9PXM
More data for this
Ligand-Target Pair