BDBM18207 (1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one::US10869929, Compound Dexamethasone::US11554172, Compound Dexamethasone::dexamethasone::dexamethasone (tetramethyl-rhodamine conjugated )

SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

InChI Key: InChIKey=UREBDLICKHMUKA-UHFFFAOYSA-N

Data: 25 KI  110 IC50  4 Kd  43 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 180 hits for monomerid = 18207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2 (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	610	n/a	n/a	n/a	n/a	8.0	25
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Phospholipase A2 group V (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	620	n/a	n/a	n/a	n/a	7.5	25
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TSC22 domain family protein 3 (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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Mineralocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
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Progesterone receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, inducible (Mouse)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Rat)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glucocorticoid receptor (Rat)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glucocorticoid receptor (Rat)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucocorticoid receptor (Rat)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
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Phospholipase A2, membrane associated (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
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Pyruvate carboxylase, mitochondrial (Homo sapiens)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Glucocorticoid receptor (Rat)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Rat)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Progesterone receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.510	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
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Phospholipase A2, major isoenzyme (Pig)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1/2 (Sheep)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase A2 (Rat)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM18207 (dexamethasone (tetramethyl-rhodamine conjugated ) ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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