BDBM182361 US9145392, 62
SMILES Nc1ncnc(N2CCC(CC2)c2nc(cn2CCN2CCCCC2)-c2ccc(F)c(c2)C(F)(F)F)c1-c1ccc(F)cc1
InChI Key InChIKey=DUXGYYIANJMODE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 182361
Affinity DataIC50: 350nMpH: 7.5Assay Description:A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv...More data for this Ligand-Target Pair
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Emd Serono Research And Development Institute
Curated by ChEMBL
Emd Serono Research And Development Institute
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair